Two people were shot and two others hurt on Tuesday when at least one gunman opened fire at a mall in the San Francisco suburb of San Bruno before apparently fleeing on a nearby train, police said.
Few official details of the shooting were immediately available.
Two gunshot victims were brought to San Francisco General Hospital and Trauma Center, while two other victims, who suffered minor injuries while fleeing from the gunman, were transported to other medical facilities, hospital spokesman Brent Andrew said in a television interview with ABC News affiliate KGO-TV.
San Bruno Police Chief Ed Barberini told reporters that "It was a senseless act," adding that opening fire in a crowded shopping mall near a Bay Area Rapid Transit (BART) station showed a "true disregard for human life."
Barberini said police were searching for one or possibly two gunmen who may have fled the scene by getting on a BART train headed for Oakland.
One employee of a shop inside the mall, Angelica Castro, said she saw a “mob of people running” toward her store from the opposite side of shopping center while they were “screaming ‘shooting, shooting, shooting,’ and their faces just had terror.”
CBS affiliate station KPIX said the shooting unfolded at the Tanforan Mall, a shopping center where a witness reported hearing eight gunshots and seeing at least two gunshot victims on the second floor, along with three people in handcuffs.
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Local media said the shopping mall in San Bruno, located south of San Francisco, was closed after the gunfire.
The Bay Area Rapid Transit authority said one of its commuter stops was shut down as a precaution after the shooting.