U.S. President Donald Trump is cautioning people in Irma's path to "get out of its way" and not worry about possessions.
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Trump says property is replaceable but lives are not, and that safety must come first.
He says the nation is grieving for those who've been killed by the powerful storm, which spent the week churning its way across the Caribbean, leaving death and destruction in its wake. Hurricane Irma is forecast to hit Florida's southern coast at daybreak Sunday.
Trump says the U.S. is as prepared as it can be for a storm as monstrous as Irma.
Trump spoke at a weekend Cabinet meeting at the Camp David presidential retreat in Maryland. He posted a brief video of his remarks on Twitter.
More than 75,000 people have flocked to shelters in Florida to escape Hurricane Irma's potentially deadly winds and storm surge. The brunt of the hurricane, one of the fiercest Atlantic storms in a century, is due to arrive in Florida early Sunday.