Israel struck targets near the Syrian cities of Homs and Tartus on Monday, wounding two soldiers and causing material damage, Syrian state media reported.
"Hostile targets" were intercepted over Homs, SANA initially said, while defense systems were also activated in the port city of Tartus.
The Syrian military said in a statement that the attack came from north of Beirut and that air defenses managed to shoot down most of the missiles used.
The British-based Syrian Observatory for Human Rights confirmed the strikes took place, adding that the attacks in Homs targeted military sites tied to the regime and Iranian militias.
Last week, Syria’s military said Israel has carried out an air raid that hit a military post on the outskirts of the capital of Damascus, causing only material damage.
However, at the end of October, five people were reportedly killed in a rare daytime missile strike outside Damascus, according to a Syrian rights watchdog. The attack was attributed by Syrian state media to Israel.