An 18-year-old Palestinian identified as Iman Munir Shubir succumbed to his wounds on Saturday after he was wounded gravely by a bullet that hit him in the stomach during protests at the border between Israel and Gaza, Gaza's Health Ministry said.
Shubir, who hails from the city of Deir al-Balah, was hurt while participating in a demonstration east of the Palestinian refugee camp of al-Bureij in the center of the Strip.
His death brings the death toll from Friday's Gaza demonstrations to four.
The three other fatalities from Friday's clashes between Gazan protesters and Israeli security forces are the 16-year-old Mohammad al-Jahjuh, who was shot east of Gaza City; the 40-year-old Maher Yasin, who was shot east of al-Bureij and the 28-year-old Abed al-Aziz Sharia, who was shot east of Gaza.
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According to Gaza authorities, Yasin suffered from mental and cognitive disablities.
At least 40 other people were wounded by live Israeli fire, and three were injured from tear gas inhalation.
The Israeli militarty said around 8,000 Palestinians gathered near the border fence on Friday: Most kept their distance, while some burned tires and tried to throw an explosive device into Israel, though unsuccessfully.
"Troops responded with riot dispersal means and fired in accordance with standard operating procedures," an Israeli military spokeswoman said.
Since the Gaza border protests began in March, around 240 Palestinians died in confrontations with the Israeli military.
Ramallah's Health Ministry reported last week that an 18-year-old resident of the refugee camp Jalazone was killed by live Israeli fire during altercations between the Israeli military and Palestinians in the West Bank.
According to the health ministry, two other Palestinians were wounded by live fire and were evacuated to a hospital in the West Bank to receive medical care.
Reuters contributed to this report.