Kofi Annan, attends an Arab ministerial committee meeting in Doha to discuss Syria, June 2, 2012.
Kofi Annan, UN-Arab League envoy to Syria, attends an Arab ministerial committee meeting in Doha to discuss the Syrian crisis on June 2, 2012. Photo by AFP
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International mediator Kofi Annan said on Friday he was "optimistic" that ministerial crisis talks on Syria being held on Saturday would produce an acceptable outcome.

"I think we are going to have a good meeting tomorrow (Saturday). I am optimistic," Annan told Reuters TV in Geneva after Russia proposed changes to his plan for a national unity government. The talks would end "with an acceptable result," he said.

His spokesman Ahmad Fawzi said: "The talks are on course and the preparatory meeting is going ahead this morning (Friday)."

Meanwhile, U.S. Secretary of State Hillary Rodham Clinton and Russian Foreign Minister Sergey Lavrov were heading for a face-to-face showdown over Syria on Friday as the major powers prepared for the weekend meeting to hash out the political transition plan for the Syria.

On the eve of Saturday's conference aimed at ending 16 months of brutal violence in Syria, Clinton and Lavrov were to meet in St. Petersburg in a bid to iron out deep differences over the transition plan being pushed by UN envoy Kofi Annan that calls for the formation of a national unity government that would oversee the drafting of a new constitution and elections.

U.S. ¬officials are adamant that the plan will not allow Syrian President Bashar Assad to remain in power at the top of the transitional government, but Russia insists that outsiders cannot dictate the ultimate solution or the composition of the interim administration.

Annan's plan would allow some members of the current regime to stay in place but would exclude those deemed to be counterproductive or destructive to the transition process, which would be Syrian led, according to diplomats familiar with the proposal. It does not explicitly bar Assad, but the U.S.¬and other western powers who will participate in the conference in Geneva say that is implicit.

The difference in interpretation could prove its unraveling and Clinton hopes to press Lavrov on the point at their meeting and over dinner following a gathering of Asia-Pacific foreign ministers that Lavrov is hosting in St.¬Petersburg.

On Thursday, Lavrov acknowledged that a transition period is necessary to end the violence in Syria, but said Russia had not agreed to all elements of Annan's plan, in particular any suggestion that Assad would be required to leave.

"We are not supporting and will not support any external meddling," Lavrov said. "External players must not dictate ... to Syrians, but, first of all, must commit to influencing all the sides in Syria to stop the violence."

He also said the Annan plan was still a work in progress.

But, Clinton, speaking Thursday in Riga, Latvia, said it was "very clear" that all participants in the Geneva meeting … including Russia … were on board with the transition plan. She told reporters that the invitations said made clear that representatives "were coming on the basis of (Annan's) transition plan."

She said she expects the meeting "to provide an opportunity to make real progress" on that plan.

Diplomatic hopes have rested on Russia … Syria's most important ally, protector and supplier of arms … to agree to a plan that would end the Assad family dynasty, which has ruled Syria for more than four decades.