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SAN DIEGO - Los Angeles pitcher Chad Billingsley came within two outs of a complete game, striking out 11 to lead the Dodgers to a 6-0 win over the San Diego Padres in the National League on Friday.

Billingsley reached double digits in strikeouts for the ninth time in his career. Andre Ethier drove in four runs with a double and triple.

The Padres now have five errors in their first two games. They've struck out 18 times in 18 innings. San Diego was shut out 19 times last year, the most in the majors.

In Milwaukee, David Freese hit a two-run drive for one of four St. Louis homers off Yovani Gallardo as the visitors spoiled Milwaukee's opener. Yadier Molina, Carlos Beltran and Matt Holliday also connected for the Cardinals.

Ryan Braun was 0 for 5 but received a rousing ovation - a show of support for the National League MVP, whose potential 50-game suspension for a positive drug test was overturned before the season.

In Phoenix, Chris Young and Paul Goldschmidt hit first-inning homers off Tim Lincecum as Arizona opened the defense of its NL West title with a win over San Francisco. Ryan Roberts' two-run double broke a sixth-inning tie as Arizona beat Giants ace Lincecum for the fourth time in a row.

In Houston, pinch runner Eric Young scored the go-ahead run on an error in the eighth inning and Colorado held on to beat the Astros. Troy Tulowitzki added a solo shot.

Over in the American League, Los Angeles pitcher Jered Weaver struck out 10 in eight innings to lead the Angels to a 5-0 win over the Kansas City Royals. Weaver finished with double-digit strikeouts for the 12th time in his career.

Peter Bourjos' bases-loaded infield single broke open a scoreless game in the eighth; that was followed by Erick Aybar's bases-loaded triple. Los Angeles' $240-million signing Albert Pujols went 0 for 3 despite several raucous ovations.

In St. Petersburg, Carlos Pena hit a grand slam in the first then completed a ninth-inning comeback that lifted Tampa Bay to a season-opening win over New York.

The Yankees' Mariano Rivera had been 60 of 61 in save chances against the Rays, but after Desmond Jennings opened the ninth with a single, Ben Zobrist tripled home the tying run.

The 42-year-old Rivera intentionally walked the next two batters to load the bases and struck out one. But Pena, who was 0 for 11 in his career against Rivera, drove a 1-2 pitch for his fifth RBI of the game.

In Arlington, Colby Lewis struck out nine as Texas spoiled the debut of new Chicago manager Robin Ventura. Ian Kinsler hit a solo homer in the third.

In Baltimore, Jake Arrieta pitched seven scoreless innings to lead the Orioles to victory over Minnesota to mark the 20th anniversary of the opening of Camden Yards. Nick Markakis hit a two-run homer in the first and added an RBI triple in the sixth.

In Oakland, Chone Figgins had three hits and two RBIs as Seattle beat the A's. Kyle Seager's two-run single highlighted a four-run third for the Mariners.