If Israel can live with a nuclear Pakistan, which remains vulnerable to an extremist pro-Taleban, Sunni takeover, I can't see why it can't live with a nuclear Iran, under a rather less extremist version of Shi'ism. Yes, it would be unpleasant. But living in Britain in the 1950s was uncomfortable, with Krushchev threatening to sink the place on the first day of war. I don't recall losing any sleep over it, though. If I was an Iranian, whether or not I approved of the mullahs,I would want my country to be nuclear armed. Not only would I be aware of being surrounded by other (and inherently or potentially hostile) nuclear states (Russia, China, Pakistan, India, Israel, the US sixth fleet and potentially Saudi Arabia). I would also be aware of how the absence of nuclear weapons facilitated the invasion of Iraq. What's needed is a different regime in Teheran, which doesn't consider itself at war with Israel or the West, but which still might want nuclear weapons.
U.S. says working on initiative to de-escalate Syria fighting, with focus on Aleppo (Reuters)
from the article: Equating Iran nukes with Holocaust highlights Israel's isolation