That the USA will be the sole broker for negotiations in the ME. Why? Because Israel is a domestic policy issue in America and not a foreign policy issue. Most of American Jews are more diehard Zionists than Israel itself and they think that they know better what Israel needs than Israel itself and insist by pressuring US government to maintain an Israel first policy right or wrong. This makes the US an unfair and biased broker. Examples of this bias in history abound.....
French tourist arrested for waving Israeli flag on Temple Mount (Haaretz)