Israel and the US probably cooperated under the Bush administration on regime change in Iran. There are a number of online articles from reputable sources, UK News, of Bush seeking regime change in Iran. Iraq was the first campaign for Bush and Iran was next . Bush hoped to have major bases in Iraq to protect US. interest in the area. Spies were a necessary part of the effort. So Iran had reason to believe Israel and the US were working against Iran.
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from the article: Iranian 'Mossad agent': I was trained in Israel