The US doesn't need Israel. It's not clear how the US actually benefits from a relationship with a country that costs them billions of dollars each year in financial aid and can only ever weaken its relationships with other countries in the region like Saudi Arabia, that the US needs to be on good terms with to maintain its energy security (e.g. the 1973 War and the oil embargo that almost crippled the US military in SE Asia). Israel is a 'strategic burden' on the US.
U.S. Democratic Senator Merkley airs support for Iran nuclear deal (Reuters)
from the article: Obama's turnabout