When the USA dropped atomic bombs on Hiroshima and Nagasaki the fallout from the explosions was thousands of miles away from themselves. There was little fear of contamination to the USA. Today the power of nuclear weaponry is more than ten fold of what used to be. The hotspots of the Middle East are so close to one another that any nuclear explosion will have far reaching ramifications for any of the countries dumb enough to explode one. Be it Israel, Egypt, Jordon, Lebanon, or Syria. Iran is the furthest away but dropping one on Israel will wipe multitudes of people off the earth. Jews and Arabs alike as well as those who have nothing to do with the conflict except that they work and live in these hotspots.
Yemen's Houthi rebels commit to peace plan in letter to UN chief, BBC reports (Haaretz)