The missile was fired from an aircraft at the car nothing was fired at the aircraft. Killing individuals are not America's style. Most probably this thing was destroyed by an Israeli combat UAV. Israel already once destroyed a convoy of weapons in Sudan using a UAV so was probably the same tried and tested solution to the problem.
Netanyahu: Most of Americans see eye to eye with Israel on dangers of Iran deal (Haaretz)
from the article: Sudan accuses Israel of carrying out air strike on Port Sudan