Of all the nations in the region, Iran can do America the most hurt and also do them the most help. Israels agenda does not match Americas agenda. At some point in time, America will have to take action against their hostile "partner". The best thing that could be done is to isolate Israel and welcome Iran into the fold. At least Iran can pay their own way and is not dependent upon American money and political support.
Germany warns of possible attacks on public transport in Istanbul (Reuters)
from the article: Iran is regional superpower even without nukes