1) Makes Iran and other countries more likely to band together for economic (nuclear, etc) projects, against the United States. 2) Makes a Sunni Shia alliance, already inevitable, much closer. 3) Forces Pakistanis to choose a side. They have. 4) Gives urgency and weight to the efforts of numerous countries, including China, to undercut the dollar as reserve.
Fear of rioting, disorder at Temple Mount prompt restrictions on Muslim worshiper (Haaretz)
from the article: Ban Ki-moon says sanctions having significant effects on Iranians