In order for Israel to succeed, it must "take out", all possible contingencies, including immediate, intermediate and long range possible responders. There is no doubt that Israel's many enemies and those that trade with Iran will try to stop Israel. The cost of this move will be expensive, both in numbers killed and alienation with western powers, especially the US. It could well turn into an armageddon. Think carefully and plan well and completely. You will only have one chance.
U.S. confirms ISIS computer expert killed in air strike (Reuters)