Several episodes of the hit animated series The Simpsons have dealt with Jewish issues, and even the Middle East conflict over the years. However, it wasn't until the series' 21st season that Homer, Marge, Bart, Lisa and Maggie will finally visit Israel and meet a bitter and angry Israeli tour guide, played by Sacha Baron Cohen (whose characters Bruno and Borat have made him a household name.)

In the episode, tentatively set to air in the U.S. on March 28, 2010, the Simpsons find themselves in Israel, and Homer develops Jerusalem Syndrome and becomes convinced that he is the messiah.

Simpsons producer Al Jean told Entertainment Weekly that Baron Cohen will partake in aggressive dialogue with Marge Simpson. "He's trying to get Marge to give him good grades on the comment card, and she goes, 'You people are pushy,' and he goes, 'What do you mean, you people? You try having Syria for a neighbor! What do you have -Canada?'" Jean said in an interview.

The episode, named "The greatest story ever D'ohed," is scheduled to coincide with Palm Sunday. "It'll be a show that all faiths can come together and be offended by," Jean promised fans of the show.