Iranian Foreign Minister Manchour Mottaki declared Monday that Israel was now weaker than ever before, adding that it was a "crazy country run by crazy people."

Mottaki told the Al-Jazeera news agency that Israel was in no position to embark on another military conflict, due to its internal political crisis and its losses over recent years in Lebanon and the Gaza Strip.

"Israel is a crazy nation run by crazy people," Mottaki declares. "Therefore, we must prepare for the chance that Israel will do something crazy against everyone in the region ? the Syrians, the Lebanese and the Palestinians."

When asked what would happen should Israel attack Iran, Mottaki replied: "Iran's position is known by everyone. We can defend ourselves." The Iranian foreign minister added that the Islamic Republic would "stand by our Arab brothers" should Israel attack any of its neighbors.

Mottaki's remarks came after Iran's Supreme Leader Ayatollah Khamenei said that Western support of Israel was ineffective, telling a top Palestinian militant leader that its obliteration was imminent according to the will of God.

"Today Palestine is the symbol of life, determination, faithfulness, diligence, and dignity," Ayatollah Khamenei told Ramadan Abdullah, the secretary general of the Palestinian Islamic Jihad Movement.

He praised the Palestinian resistance movement and declared that it had proven itself stronger despite the military superiority of the Israel Defense Forces.

In his comments, Khameini joined a long list of top Iranian officials, especially President Mahmoud Ahmadinejad who have said on several occasions in the past that Israel should be destroyed.

Last year, Ahmadinejad said that Israel was "dying" and that people in the Middle East would destroy it if given the chance and stressed that opposition to Israel is a fundamental principle in Shi'ite Muslim Iran.

"They should know that regional nations hate this fake and criminal regime and if the smallest and briefest chance is given to regional nations they will destroy [it]," said Ahmadinejad, who often rails against Israel and the United States.

A 2005 statement by Ahmadinejad saying that "Israel should be wiped off the map" outraged the international community.

Also, a senior Iranian army commander said Iran will respond to any military attack from Israel by "eliminating" it, in comments condemned by Washington.