Life, film, comedy – and Jews – came hilariously, if not awkwardly, together on Saturday night as Facebook founder Mark Zuckerberg came face to face with both the Hollywood actor who recently portrayed him on the big screen as well as a comedian who regularly lampoons him on the silver one.

Making what could count as his comedy debut, the Facebook chief joined the opening monologue of the popular NBC skit show Saturday Night Live, accompanying Jesse Eisenberg – nominated for an Academy Award for his portrayal of Zuckerberg in the critically acclaimed "The Social Network."

Rounding off the potentially awkward trio was SNL cast member Andy Samberg, who has regularly imitated the Facebook founder in several of the show's episodes.

Opening the show's monologue as the night's featured guest, Eisenberg was promptly interrupted by Samberg, only to be finally outdone by Zuckerberg himself.

"Why can't I go in there? I'm the real Mark Zuckerberg," Zuckerberg could be heard asking the show's creator and executive producer Lorne Michaels, adding: "Those guys are such nerds. Come on, I invented poking."

Samberg's exited quickly, leaving Zuckerberg and Eisenberg to enact what could have been a real-life awkward meeting.

"So?" Eisenberg said.

"So?" Zuckerberg replied. "I really liked you on '60 Minutes.'"

"Thanks, man."

Eisenberg then inquired: "You ever end up seeing the film 'The Social Network'?"

"Yeah, I did," replied Zuckerberg.

"Cool. Thanks. And what did you think?"

"It was interesting," Zuckerberg replied.

"Interesting? You know, I'll take it."

Eisenberg is nominated for an Academy Award for his portrayal of Zuckerberg in "The Social Network," with some considering him the front runner in a star-studded field of nominees.